AMGEN INC

CUSIP: 31162100 Class: COMMON STOCK

SPHERA FUNDS MANAGEMENT LTD.'s Holding History (CIK: 0001496201)

Note: Option positions (PUT/CALL) are excluded.

Q2 2016
Shares 85,000 Value ($000) $12,933 Avg Close — Range —
Q4 2014
Shares 8,550 Value ($000) $1,362 Avg Close — Range —
Q3 2014
Shares 48,550 Value ($000) $6,819 Avg Close — Range —
Q2 2014
Shares 40,000 Value ($000) $4,735 Avg Close — Range —
Q1 2014
Shares 70,000 Value ($000) $8,634 Avg Close — Range —
Q4 2013
Shares 70,000 Value ($000) $7,991 Avg Close — Range —